(Ultracain™, Septanest™, Citocain™, Primacaine™, Septocaine™, Ubistesine™, Alphacaine™)
Advantages
Characteristic for articaine HCl is
that they are fast acting and effective in penetrating bone. The latter
has
not been proven scientifically but is the opinion of those who work
with these products. When using articaine HCl,
the patient no longer has to return to the waiting room to allow the
anesthetic
to take effect. During treatment, it seems as though articaine HCl
are more effective than most other anesthetics. For these reasons,
increasing numbers of dentists and dental surgeons
are
opting for articaine HCl.
Disadvantages
Articaine is dependent on cholinesterase group enzymes to
metabolize correctly and in particular pseudocholinesterase (PChE),
also known
as ButyrylCholinesterase (BuChE). When there are insufficient levels
of this enzyme or insufficiently effective enzymes in the body, articaine
HCl are not broken down in the way intended and the body seeks alternative
ways to rid itself of these substances. This alternative
metabolic process leads to the formation toxic by-products, which can
cause paralysis or brain damage. In some cases, these by-products attack
the human DNA/RNA structure, which can cause the onset of cancer. The
forms of cancer evoked by articaine are, in our experience, particularly
aggressive and resistant to therapy. The cancer
can be treated by means of chemotherapy, radiation treatment or surgery
but tends to return after a while because the articaine that has accumulated
in tissue, fat or brain tissue, is slowly released back into the body.
If the immune system has been weakened, due to use of medicines, stress
or an unhealthy lifestyle, the cancer can return as a result of the
steady release of unprocessed, or partially processed, articaine in
the body tissues.
The latest experiential results indicate that articaine may distort the metabolism of fatty acids. The editors will update these pages as more information about and insight into these unsuspected side effects become available.
Glossary resistance to therapy: quite often it is noted that therapies designed to combat the symptoms of certain conditions fail with victims of articaine. In the opinion of the Bosscher Foundation, this is because damaging substances (articaine or its by-products) remain in the human body and can be re-released at any moment, causing the symptoms to reoccur, even after initially successful treatments. Click here to return.
